Semaglutide is a synthetic GLP-1 (glucagon-like peptide-1) receptor agonist that has become the gold standard for incretin-based research. Its unique molecular structure includes two key modifications that dramatically extend its half-life to approximately one week.
Mechanism of Action:
Semaglutide binds to and activates GLP-1 receptors in the pancreas, brain, and gastrointestinal tract. This activation stimulates glucose-dependent insulin secretion, suppresses glucagon release, delays gastric emptying, and activates satiety centers in the hypothalamus.
Technical Specifications:
• CAS Number: 910463-68-2
• Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
• Molecular Weight: 4113.64 g/mol
• Amino Acids: 31
• Purity: >98% (HPLC verified)
• Form: Lyophilized powder
• Storage: 2-8°C, protect from light
Research Applications:
Extensively studied for glycemic control, cardiovascular outcomes, and weight management research. Published clinical data supports its use in metabolic and cardiometabolic investigation.
For research purposes only. Not for human consumption.